For years, you’ve probably heard about collagen, the protein that helps keep your skin firm, smooth, and youthful. But there’s another molecule that’s just as important, if not more: NAD+ (nicotinamide adenine dinucleotide). It lives in every single one of your cells and acts like fuel. Without it, your body can’t produce energy, repair DNA, or keep your skin and organs working the way they should.
NAD+: the powerful anti-aging enzyme
Why does NAD+ matter as you get older?
Your NAD+ levels naturally go down with age. By the time you’re in your 40s or 50s, your body has far less NAD+ than it did when you were younger. This drop doesn’t just leave you feeling more tired, it also shows up in your skin. Fine lines, sagging, and a duller complexion are all linked to lower NAD+.
Science and studies show that NAD+ is a key player in how your skin ages. Every day, your skin faces UV rays and environmental stress that damage DNA. Normally, your body has repair systems to fix this damage fast. When NAD+ runs low, your skin can’t repair DNA as effectively. That damage builds up, which leads to aging from the inside out.
How does low NAD+ change your skin cells?
Low NAD+ also contributes to something called cellular senescence. That’s when skin cells stop dividing and working normally. Senescent fibroblasts (cells that normally make collagen and elastin) just sit there, alive but unhelpful. Instead of keeping your skin strong and bouncy, they release inflammatory molecules that actually break down collagen and thin your skin. Research shows that restoring NAD+ can reduce these senescent cells and help your skin repair itself better.
How does NAD+ fit with other skin treatments?
At Chicago Aesthetics, we often combine NAD+ therapy with treatments like Radiesse or Sculptra, which stimulate collagen. Together, they give your skin both the structure (collagen) and the energy (NAD+) it needs to stay firm, radiant, and youthful. This combination addresses aging at its root-not just at the surface.
NAD+: the powerful anti-aging enzyme
Why do we recommend NAD+ to support your skin and overall health?
NAD+ is much more than a trend. It’s a core molecule that helps repair DNA, protect collagen, recycle damaged proteins, and keep your skin strong as you age. By restoring NAD+, you’re giving your body and skin the tools they need to function like they did years ago. So whether you’re looking to restore energy, get smoother skin, or want to improve your long-term health, NAD+ may be a great option.
Ready to Book?
Schedule your complimentary skin consultation today ($50 value). Call or Text us 312.846.1629 or visit our contact page to request your appointment online.
New Patients: 20% off any aesthetic med spa treatment (only available with select providers). Contact our office for details. See our monthly specials.
